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If a liver extract capable of carrying out normal metabolic reactions (including gluconeogenesis) is incubated with labeled pyruvate labeled with oxygen-18 as shown below, where would the label be found in glucose? Explain, including schemes of the reactions to support your answer. In order to effectively show where the label ends up, you do not need to show mechanisms, but you must show schemes to fully keep track of the label. An example of what I'm looking for in the first step is shown to help you work this problem.

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