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Http://learn.genetics.utah.edu/content/begin/dna/prions/index.html

After browsing Prusiner's paper and/or checking out the website mentioned, are you convinced that prions can be infectious agents? Why or why not? Also, given what you've learned on protein folding and secondary structure, what are the implications of the change of secondary structure of the PrPC protein from very little B-sheet to PrPSC containing 45% B-sheet?

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