Consider a deleterious recessive allele at a frequency of q = 0.0016 in the population.
a. How many times more likely is the offspring of a cousin mating to suffer its effects (that is, to be homozygous for it) than is an outbred individual?
b. Now do the same analysis for recessive alleles at lower (q = 0.0005) and higher (q = 0.05) frequencies. For which kinds of alleles does inbreeding most strongly increase the probability (absolutely, and relatively) of being affected by the mutation?