Citrate synthase catalyzes the reaction: oxaloacetate + acetyl-CoA <--> citrate + HS-CoA; delta G'(superscript o) = -31.5 kJ/mol
Malate dehydrogenase catalyzes the reaction:
malate + NAD+ <--> oxaloacetate + NADH + H+; delta G'(superscript o) = 29.7 kJ/mol
How does the citrate synthase reaction influence the malate dehydrogenase reaction? What is the overall change in Free Energy for the two reactions?