10. Which of the following is an example of cross-presentation?
A. An endogenous peptide being presented on MHC class I
B. An exogenous peptide being presented on MHC class I
C. An endogenous peptide being presented on MHC class II
D. An exogenous peptide being presented on MHC class II
E. A B-cell antigen being presented to a T cell
11. Hematopoietic stem cells cultured in the presence of which receptor differentiate into T cells rather than B cells?
A. T cells
B. B cells
C. Notch-ligand
D. CD3
12. Which of the following molecules would double-negative T cells
fail to express?
A. CD3
B. CD4
C. MHC class I
D. TAP
E. All of the above
13. At what stage of T cell development is the pre-TCR
expressed?
A. Double negative
B. Double positive
C. Single positive
D. Pro-T cell
14. What happens to autoreactive cells that escape the thymus?
A. They attack self tissues.
B. They can be rendered anergic
C. They negatively regulate other autoreactive cells
D. They require TCR-ligation and costimulation to be activated.
E. All of the above
4. What happens to autoreactive cells that escape the thymus?
A. They attack self tissues.
B. They can be rendered anergic
C. They negatively regulate other autoreactive cells
D. They require TCR-ligation and costimulation to be activated.
E. All of the above
15. At what stage of T cell development is the pre-TCR
expressed?
A. Double negative
B. Double positive
C. Single positive
D. Pro-T cell
E. None of the above
16. In negative selection, cells that receive _____________ signal
through their antigen receptors die.
A. A weak
B. A Strong
C. An Intermediate
D. No
17. What happens to autoreactive cells that escape the thymus?
A. They attack self tissues.
B. They can be rendered anergic.
C. They negatively regulate other autoreactive cells.
D. They require TCR-ligation and costimulation to be activated.
E. All of the above
18. TREGs have been shown to be protective against which of the
following conditions?
A. Inflammatory Bowel Disease
B. Influenza
C. Malaria
D. HIV
E. MRSA 19. Ligation of which of the following cell-surface receptors leads to
cell death?
A. TCR
B. TLR
C. Fas
D. Caspase 8
20. How long does B cell maturation from an HSC to a mature B
cell take?
A. 1-2 Hours
B. 1-2 days
C. 1-2 weeks
D. 1-2 months
21. This type of cell will leave the bone marrow and complete
maturation in the spleen.
A. Common lymphoid progenitor cell
B. Hematopoietic stem cell
C. Immature B cell
D. Pro-B cell
E. Pro-T cell