Fill in the blank:

Glycosylation is an important modification in the cell biochemistry.

a. Glycans are ___________.

b. The Glycome is __________________________________, is estimated to be _________________________ larger than the proteome.

c. Glycosylation is addition of glycans to _________________ and lipids.

d. The term of CDGs is congenital disorders of glycosylation, which affects N-linked glycosylation. The CDGs have been classified into two classes: Type 1 involves defects in _____________________________; Type 2 involves defects in _________________________________.

e. For protein glycosylation, the N-linked adds glycans to the amino acid of ____________________, which is initiated in __________________; while the O-linked adds glycans to the amino acids of __________________ and _______________________.