1. Gennie is wild type. Below is a segment of her DNA. The top strand is the coding region, and the reading frame begins with the first codon that codes for met (start codon).
5' GCATGTTCTTGT 3'
3' CGTACAAGAACA 5'

Kevin is mutant. Below is a segment of his DNA. The top strand is the coding region, and the reading frame begins with the first codon that codes for met (start codon).
5' GCATGTTTTTGT 3'
3' CGTACAATAACA 5'

What type of mutation does Kevin have?
A) silent
B) misssense
C) nonsense
D) frameshift

2) A type of dwarfism results from the production of mutant SHR-1 protein. You look at the length of the mutant SHR-1 and the normal (wild-type) SHR-1 protein, and discover that the mutant SHR-1 protein has fewer amino acids.

What do you expect to find when you examine the DNA sequence?
A) nucleotides were deleted
B) additional nucleotides were added
C) one nucleotide was changed
D) without additional information, any of the above are possible.

3) Below are two DNA coding strand sequences. The 5' ATG encodes the in-frame strat codon.
Tom's DNA sequence is:
5' ATG CGC TTA CCC TTA CTC CTA TAA 3'

Harry's DNA sequence is:
5' ATG CGC TAA CCC TTA CTC CTA TAA 3'

Harry's mutation causes the premature termination of:
A) Replication
B) Transcription
C) Translation
D) Answer B and C
E) All of the above