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Fumarase deficiency is an extremely uncommon disease in humans. People with this disease can survive though they are significantly influenced.

a) Given the significance of fumarase to the citric acid cycle describe how is it possible for people with fumarase deficiency to produce sufficient ATP for survival?

b) What would be the overall effect of this deficiency for fuel catabolism in these people?

c) What would be the expected impact of this disease on the urea cycle?

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