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Question: For many years the benefits of routine use of female hormone supplements (estrogen + progesterone) by postmenopausal women have been debated. An American study, the "Women's Health Initiative", compared 8506 women randomized to taking daily hormone supplements to 8102 women randomized to placebo (JAMA 2002;288:321-33). The results were against (positive) expectations.

Results

Hormone supplements (n = 8506)

placebo

(n = 8102)

Average follow-up in months (standard deviation)

62.2 (16.1)

61.2 (15.0)

Cardiovascular disease

695

546

Cancer

502

458

Fractures

650

788

Died

231

218

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Biology, Academics

Category:- Biology
Reference No.:- M9353019

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