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Mom Smith is heterozygous for an X-linked trait that can be recognized by a polymorphism when her DNA is cut with Hae III and probed with ExTend probe. The polymorphism is a 3.5kb band for normal and a 1.5kb band for disease. Please diagram what you predict the autoradiograph would look like for the above samples if the Smith sons 1 and 4 are affected and Smith Dad, Mom Jones and Dad Jones are not affected.
1 2 3 4 5 6 7 8 9 10 11 12

-Is the Smith daughter a carrier? Explain.
-What if Dad Jones is also affected but not Mom Jones or Dad Smith?
1 2 3 4 5 6 7 8 9 10 11 12

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