describe Understanding mutation of alleles
Gene A encodes a receptor tyrosine kinase Gene B encodes a G-protein coupled receptor. All of these genes has mutant alleles that are structurally normal however lack activity in their cytoplasmic domains.
a) describe what activity does the cytoplasmic domain of a receptor tyrosine kinase normally have?
b) describe what activity does the cytoplasmic domain of a G-protein-coupled receptor normally have?
c) describe is heterozygosity for the mutant allele of gene A or gene B likely to be more serious and Why?