Ask Biology Expert

describe pharmacology

Pharmacodynamics is the term utilized to define the effect that a drug has on the body. It controls whether the drug is going to be actual in the treatment of disease with the minimum of side-effects. The initial step leading to a drug response is the binding of a drug to its receptor. This drug receptor interaction is followed by a sequence of intracellular events that results in the response of the cell to the drug.

Pharmacokinetics is the term is used to label the effect the body, its organs and tissues has on the action of a drug once it is administered. It is uncommon for the same amount of drug to be eventually available at its site of action. As soon as the drug arrives the body, the body will perform on the drug to change its concentration as well as in many cases its chemical structure. In order to be able to custom drugs wisely as well as at the appropriate doses we need to understand the pharmacokinetics of the drug. To exert an effect on the body a drug must spread its target tissue in a suitable form as well as in sufficient concentration to pledge a specific therapeutic effect. Once the pharmacokinetics of a drug are recognised it is then possible to determine:

• the amounts (concentrations) to be given to the patient

• the most operative route of administration

• How often the dose has to be given in order to obtain maximum therapeutic benefit for the patient.

The unique characteristics of all patient can influence both the pharmacokinetics and pharmacodynamics processes involved in the drug action. They can likewise determine the patient's response. Sources of individual variation include:

• interactions among drugs if the patient is receiving more than one drug at the same time

• physiological variables such as age sex and weight

• patho-physiological variables related to disease (especially abridged function of the kidney and liver, which are the major organs of drug elimination)

• Genetic variables which can alter the metabolism of drugs as well as predispose the patient to unique side-effects which cannot be predicted.

When we consider each of the possible uncontrolled variables associated with the treatment of an individual patient - such as the patient's disease as well as the multiple pharmacological effects of many drugs - it is easy to consider that any attempt at rational drug therapy is impossible. To the inexperienced as well as untrained student initial encounters with drug treatment may appear as the best guess on the part of the clinical team backed up by years of clinical experience of what drugs have worked in the past on patients with an alike illness. Luckily this is not true. Of all branches of practical medicine it is maybe the therapeutic aspect of patient care with drugs which is most agreeable to objective research. For ex we can:

• interfere in the patient's disease with a drug

• accurately measure the response to the drug

• Use the data attained from one group of patients to develop and inform good practice for the use of the drug in other patients.

When we administer a medicine to an enduring the active drug itself is only one variable in a complex pattern of events that will determine how that individual patient responds. It is significant, therefore that we devote time considering all of the factors that may happen to our therapeutic objective between the writing of the prescription as well as the patient's final response to the drug.

Using the above information besides information from your own sources, describe the difference among Pharmacodynamics and Pharmacokinetics in detail

Biology, Academics

  • Category:- Biology
  • Reference No.:- M917684

Have any Question?


Related Questions in Biology

Case study question -case study - mary 21 years old

Case Study Question - Case Study - Mary, 21 years old, presented to the hospital emergency department with an infected laceration on her left foot. Mary was at a beach resort four days ago, when she trod on a broken glas ...

Assignment -the upper-case blue letters are the 14th exon

Assignment - The upper-case, blue letters are the 14th exon (of 20) in the Hephl1 gene in mice. The lower-case (black) letters are from the flanking introns.  The highlighted bases indicate primers that may be used to ge ...

Question - a pure strain of mendels peas dominant for all

Question - A pure strain of mendel's peas, dominant for all seven of his independently assorting genes, was testcrossed. How many different kinds of gametes could the F1 PRODUCE?

Igfbp2 rbp4 and factor d post bariatric surgeryigfbp2 what

IGFBP2/ RBP4 and Factor D Post Bariatric Surgery IGFBP2 ( what the normal physiological action in the body? And how it affectedby obesity? andpost bariatric surgery?) RBP4 (what the normal physiological action in the bod ...

Assignment on nutrition - q1 task you need to select 2

Assignment on Nutrition - Q1. Task: You need to select 2 different age groups of your choice. You will need to plan balanced meals with snacks for a day. Once you have laid out the meal plan you need to: Explain why the ...

Question - gene cloning a please write the steps to clone

Question - Gene Cloning a) Please write the steps to clone the protease gene from Bacillus strain whose genome sequence is not known. b) Express the protease gene to obtain the enzyme in high yield, please plan your prot ...

Instructions address each question below as it relates to

Instructions: Address each question below as it relates to the caw study given. A patient was brought to the Emergency Department by ambulance with two arrow wounds. One arrow is still in the patient on the left side; en ...

Use of molecular tools and bioinforrnatics in the diagnosis

Use of Molecular Tools and Bioinforrnatics in the Diagnosis Characterization of Enteric Pathogens from a Case Study Purpose: The purpose of this project is to familiarize the student with modern molecular tools and bioin ...

Experiment 1 staining video1 open the media player by

Experiment 1: Staining Video 1. Open the Media Player by clicking on the film-strip button in the lower left of the lab's window frame, as shown below. The Media Player is a repository of images, videos, saved snapshots, ...

Chosen dr jan nolta- stem cell researcher head of uc davis

Chosen Dr. Jan Nolta- Stem Cell Researcher Head of UC Davis Stem Cell Program Director Topic Background: early Stem cells have the ability to develop into many different types of cells. Stem Cell Research is not without ...

  • 4,153,160 Questions Asked
  • 13,132 Experts
  • 2,558,936 Questions Answered

Ask Experts for help!!

Looking for Assignment Help?

Start excelling in your Courses, Get help with Assignment

Write us your full requirement for evaluation and you will receive response within 20 minutes turnaround time.

Ask Now Help with Problems, Get a Best Answer

Why might a bank avoid the use of interest rate swaps even

Why might a bank avoid the use of interest rate swaps, even when the institution is exposed to significant interest rate

Describe the difference between zero coupon bonds and

Describe the difference between zero coupon bonds and coupon bonds. Under what conditions will a coupon bond sell at a p

Compute the present value of an annuity of 880 per year

Compute the present value of an annuity of $ 880 per year for 16 years, given a discount rate of 6 percent per annum. As

Compute the present value of an 1150 payment made in ten

Compute the present value of an $1,150 payment made in ten years when the discount rate is 12 percent. (Do not round int

Compute the present value of an annuity of 699 per year

Compute the present value of an annuity of $ 699 per year for 19 years, given a discount rate of 6 percent per annum. As