Question: Explain how temperature affects the hemoglobin saturation curve. (For example, does it shift to the right or to the left in response to an increase or decrease in temperature?) How does temperature affect the delivery of oxygen to the tissues? Include the concept of hemoglobin's affinity or lack of affinity for oxygen, and how this relates to oxygen delivery to tissue.
How does pH affect the hemoglobin saturation curve? What effect do changes in pH have on the delivery of oxygen to the tissues?