A polypeptide has the following amino acid sequence:

Met-Ser-Pro-Arg-Leu-Glu-Gly
The following mutation occurs

Met-Ser-Ser-Arg-Leu-Glu-Gly

A)Determine the most likely type of change that occurred in the DNA (single-base substitution, insertion, deletion), the phenotypic effect of the mutation (nonsense mutation, missense mutation, frameshift mutation, etc) and whether it is a transition or transversion. Refer to Figure 15.10 in your text to help you figure this out.

1. abase substitution leading to a nonsense mutation, transversion mutation
2. bdeletion leading to a frameshift mutation, transversion mutation
3. cbase substitution leading to a missense mutation, transition mutation
4. dbase substitution leading to a silent mutation, transition mutation