Question: Cystic fibrosis is an autosomal recessive disorder. A female of unknown genotype (whose brother has the disease) wants to have children with a male of unknown genotype (whose sister has the disease). None of the biological grandparents of the not-yet-conceived child has the disease. If this couple has a child, what is the probability that the child will have the disease? (Draw out the pedigrees)

Question: Draw the synaptic configuration of homologous pairs of chromosomes when one member is normal and the other member has sustained a duplication within the chromosome (but not at the end of the chromosome)