Dr. j. walker meticulously prepares an sirna 22 bp duplex, Ask an Expert

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Dr. J. Walker meticulously prepares an siRNA (22 bp duplex) and transfected cultured cells. He finds that the target gene mRNA is indeed knocked down, but so are 5 other non target mRNAs. The effect is sequence-specific and not an artifact. Rationalize this finding.

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Category:- Biology
Reference No.:- M998385

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