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DIVISION PHASE OR MITOSIS (M- PHASE)

Cell division was first  observed by  Naegeli 1842 in plant cells ,but  thoroughly described by Eduard strasburger  1875. Fleming 1879 described  . it in animals  cells. The  term  mitosis was given to it by Fleming 1880. Since  the most  vital  significance of mitosis  is  a precise  duplication of genetic  material  and the latter resides  in the  nucleus  it is advisable  to divide  the whole  process into  nuclear division (= Karyokinesis) and  cytoplasmic division. Sequentially  all changes  undergone  by a cell during  mitosis  are divisible in four  main phases , viz  prophase, metaphase, anaphase and telophase .   

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