15. At what stage of T cell development is the pre-TCR
expressed?
A. Double negative
B. Double positive
C. Single positive
D. Pro-T cell
E. None of the above
16. In negative selection, cells that receive _____________ signal
through their antigen receptors die.
A. A weak
B. A Strong
C. An Intermediate
D. No
17. What happens to autoreactive cells that escape the thymus?
A. They attack self tissues.
B. They can be rendered anergic.
C. They negatively regulate other autoreactive cells.
D. They require TCR-ligation and costimulation to be activated.
E. All of the above
18. TREGs have been shown to be protective against which of the following conditions?
A. Inflammatory Bowel Disease
B. Influenza
C. Malaria
D. HIV
E. MRSA 19. Ligation of Determine which of the following cell-surface receptors leads to cell death?
A. TCR
B. TLR
C. Fas
D. Caspase 8
20. How long does B cell maturation from an HSC to a mature B
cell take?
A. 1-2 Hours
B. 1-2 days
C. 1-2 weeks
D. 1-2 months
21. This type of cell will leave the bone marrow and complete
maturation in the spleen.
A. Common lymphoid progenitor cell
B. Hematopoietic stem cell
C. Immature B cell
D. Pro-B cell
E. Pro-T cell
22. VDJ recombination occurs during which phase of a B cell's
development?
A. Activated B cell
B. Mature B cell
C. Naive B cell
D. Pro-B cell
E. Immature B cell