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Describe the nature of the enzymes involved in the phosphorylation of glucose

Phosphorylation of glucose: Glucose is converted to glucose-6-phosphate since phosphorylated intermediates do not readily penetrate cell membrane and  this  commits glucose to further metabolism in  the cell. Hexokinase catalyses this irreversible reaction'  in most tissues and in  liver glucokinase  is  the predominant enzyme  for  the phosphorylation of glucose. Hexokinase is an allosteric enzyme that  is strongly inhibited by the product, glucose-6-phosphate.

 

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