Define epigenetic mechanisms involved during embryogenesis.
In this segment, we will acquire about the epigenetic mechanisms involved during embryogenesis as well as about developmental diseases resulting from defects in genes involved in epigenetic regulation.
At the end of this segment, you will be able to
•define epigenetic changes involved in embryogenesis
•describe X inactivation and describe its mechanism
•describe gene imprinting and describe its mechanism
•name and describe 3 human developmental disorders caused by faulty epigenetics
Several epigenetic changes occur upon fertilization and during the pre-implantation stages.
•What are the insinuations of this phenomenon in embryos formed through assisted reproductive technologies?
•Do these embryos display the same or similar epigenetic modifications? Define the evidence and provide citations to support your answer