Continuous exposure of a gs protein ndashcoupled receptor, Ask an Expert

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Continuous exposure of a Gs protein –coupled receptor toits ligand leads to a phenomenon known as desensitization. Describe three mechanisms for receptor desensitization. How can a receptorbe reset to its original sensitized state? What effect would amutant receptor lacking serine or threonine phosphorylation siteshave on a cell (6 points)?

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