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Consider three loci linked in following order: A-B-C, where the A-B recombination frequency is 0.1 and B-C recombination frequency 0.05.

(a) Supposing no interference, how many expected double crossovers are seen in sample of 1000 gametes?

(b) Supposed 99% interference, how many are anticipated in the sample of 1000 gametes?

(c) Supposing 99% interference, how many gametes should be sampled to have 95% probability that we see at least one double crossover?

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