(Answered) Consider a single locus with three alleles a1 a2 and a31

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Consider a single locus with three alleles: A₁, A₂, and A₃.

1) Write down all of the diploid genotypes possible at this locus.

2) Derive the equation for the frequency of allele A₁ as a function of the genotype frequencies.

Consider the following two datasets:

At the M locus:

In a study of 1000 adults, the following genotype numbers were found:

M₁M₁ - 213 individuals

M₁M₂ - 489 individuals

M₂M₂ - 298 individuals

At the S locus:

In a study of 4555 adults, the following genotype numbers were found:

S₁S₁ - 3564 individuals

S₁S₂ - 979 individuals

S₂S₂ - 12 individuals

Assignment: For both loci

Calculate the frequency of the alleles.
Calculate expected number of each genotype if the population were in Hardy-Weinberg equilibrium.
Identify which locus most clearly violates at least one of the H-W assumptions.

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