Research has shown that rats injected with cortisol will self-administer alcohol (ethanol).
Coherence is defined as a state where body systems (most importantly the heart and brain) are in-sync. Clarity of thought and emotional balance are the result.
SERT is a 5-HTT serotonin transporter gene that has been identified in research as a contributing factor, and possible identifier, of those who would succumb to depression or anxiety disorders after periods of chronic stress, and those who would not.
SERT appears to be activated by chronic low grade cortisol baths.
Because of its reactivity, the genetic predisposition to depression and anxiety due to the short form of SERT, may also predispose a person to significant improvement through intervention.
The brain will actually produce more receptor sites for cortisol if it is exposed to constant ‘cortisol baths'.