Canine phosphofructokinase pfk deficiency afflicts springer, Ask an Expert

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Canine phosphofructokinase (PFK) deficiency afflicts springer spaniels, affecting an estimated 10% of the breed. PFK is the glycolytic enzyme that phosphorylates fructose-1-phosphate and catalyzes the committed step in glycolysis. Given its critical role in glycolysis, one implication of the genetic defect resulting in PFK deficiency in dogs is

a. elevated blood-glucose levels in the dog's blood
b.an intolerance for exercise
c.a reduced life span
d. early embryonic mortality

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Category:- Biology
Reference No.:- M9399261

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