Ask Question, Ask an Expert

+1-415-315-9853

info@mywordsolution.com

Ask Biology Expert

1. Electron transport translocates protons from the mitochondrialmatrix to the external medium, establishing a pH gradient across the inner membrane (outside more acidic than inside). The tendency of protons to diffuse back into the matrix is the driving force for ATP synthesis by ATP synthase. During oxidative phosphorylation by a suspension of mitochondria in a medium of pH 7.4, the pH of the matrix has been measured as 7.7.
a. find out [H+] in the external medium and in the matrix under these conditions.
b. What is the outside: inside ratio of [H+] ? Is there energy inherent in this concentration? describe.
c. find out the number of protons in a respiring liver mitochondrian, assuming its inner matrix compartment is a sphere of diameter of 1.5 micro meter.

2. find out:
a. The protonmotive force across the inner mitochondrial membrane at 25 degree celsius when the elcetrical difference is -0.18 V (inside negative), the pH outside is 6.7, and the pH inside is 7.5.
b. The percentage of energy from the chemical (pH) gradient and the percentage from the charge gradient.
c. The total free energy available for the phosphorylation of ADP.

3. In the presence of saturating amounts of oxaloacetate,the activity of citrate synthase from pig heart tissue shown a sigmoid dependence on the concentration of acetyl-CoA. When succinyl- CoA is added, the curve shifts to the right and the sigmoid dependence is more produced.
a. On that basis of those observations, suggest how succinyl- CoA regulates the activity of citrate synthase.
b. Why is succinyl - CoA an appropriate signal for the regulation of the citric acid cycle?
c. How does the regulation of citrate synthase control the rate of cellular respiration in pig heart tissue?
4. Electron transport translocates protons from the mitochondrialmatrix to the external medium, establishing a pH gradient across the inner membrane (outside more acidic than inside). The tendency of protons to diffuse back into the matrix is the driving force for ATP synthesis by ATP synthase. During oxidative phosphorylation by a suspension of mitochondria in a medium of pH 7.4, the pH of the matrix has been measured as 7.7.
a. find out [H+] in the external medium and in the matrix under these conditions.
b. What is the outside: inside ratio of [H+] ? Is there energy inherent in this concentration? describe.
c. find out the number of protons in a respiring liver mitochondrian, assuming its inner matrix compartment is a sphere of diameter of 1.5 micro meter.

4. find out:
a. The protonmotive force across the inner mitochondrial membrane at 25 degree celsius when the elcetrical difference is -0.18 V (inside negative), the pH outside is 6.7, and the pH inside is 7.5.
b. The percentage of energy from the chemical (pH) gradient and the percentage from the charge gradient.
c. The total free energy available for the phosphorylation of ADP.

5. In the presence of saturating amounts of oxaloacetate,the activity of citrate synthase from pig heart tissue shown a sigmoid dependence on the concentration of acetyl-CoA. When succinyl- CoA is added, the curve shifts to the right and the sigmoid dependence is more produced.
a. On that basis of those observations, suggest how succinyl- CoA regulates the activity of citrate synthase.
b. Why is succinyl - CoA an appropriate signal for the regulation of the citric acid cycle?
c. How does the regulation of citrate synthase control the rate of cellular respiration in pig heart tissue?

Biology, Academics

  • Category:- Biology
  • Reference No.:- M924115

Have any Question? 


Related Questions in Biology

Select one of the topics research the topic thoroughly and

Select One of the Topics, Research the Topic Thoroughly and Write a Concise Research Paper Companion Animal Medicine Most of the concepts that apply to humans also apply to our companion animal friends, an important thin ...

1 how is gene expression regulated give three different

1. How is gene expression regulated (give three different forms of regulation mechanisms)? 2. How does gene regulation relate to cancer development?

Identify and give functions of the organs and structures of

Identify and give functions of the organs and structures of the urinary system.

Research and briefly describe a real world example about

Research and briefly describe a real world example about how acid rain affects plants. Be sure to demonstrate how pH contributes to the outcome, and proposed solutions (if any). Descriptions should be approximately 2 - 3 ...

The protein produced by huntingtons disease huntingtin

The protein produced by Huntington's disease (huntingtin) interferes with general transcription factor (called CBP) and prevents it from binding the promoter. CBP activates genes involved in cell survival. i) Which step ...

The ability of a person to roll their tongue is controlled

The ability of a person to roll their tongue is controlled by a single gene with two alleles. About 65% of people have the dominant allele, and can therefore roll their tongue. Stephanie cannot roll her tongue. Without y ...

Ocean systemsaccording to the law of conservation of energy

Ocean Systems According to the law of conservation of energy, energy cannot be created or destroyed, but it can change from one form to another 1. A boy doing a cannonball into the pool. He went from potential to kinetic ...

Of the four chambers of the human heart which has the

Of the four chambers of the human heart, which has the thickest walls, and why? Why can you not catch the same cold twice, but a new cold will make you sick for a week or two? What is the key step in spermatogenesis that ...

Case study 20 food for a low-income familysarah is a

Case Study 20: Food for a Low-Income Family Sarah is a 30-year-old mother of two young children, ages 3 and 5. Her husband was recently disabled in a car accident and has been unable to work for 6 months. Sarah works par ...

Huntingtons disease affects individuals late into adulthood

Huntington's disease affects individuals late into adulthood. Given what you know about how Natural Selection works, explain why Huntington's disease hasn't been eradicated from the population.

  • 4,153,160 Questions Asked
  • 13,132 Experts
  • 2,558,936 Questions Answered

Ask Experts for help!!

Looking for Assignment Help?

Start excelling in your Courses, Get help with Assignment

Write us your full requirement for evaluation and you will receive response within 20 minutes turnaround time.

Ask Now Help with Problems, Get a Best Answer

Section onea in an atwood machine suppose two objects of

SECTION ONE (a) In an Atwood Machine, suppose two objects of unequal mass are hung vertically over a frictionless

Part 1you work in hr for a company that operates a factory

Part 1: You work in HR for a company that operates a factory manufacturing fiberglass. There are several hundred empl

Details on advanced accounting paperthis paper is intended

DETAILS ON ADVANCED ACCOUNTING PAPER This paper is intended for students to apply the theoretical knowledge around ac

Create a provider database and related reports and queries

Create a provider database and related reports and queries to capture contact information for potential PC component pro

Describe what you learned about the impact of economic

Describe what you learned about the impact of economic, social, and demographic trends affecting the US labor environmen