Assume you have two cell lines named ViRa and SaSi growing in your lab. ViRa is susceptible to poliovirus infection, but is not permissive; SaSi is not susceptible to poliovirus infection, but is permissive. Note that poliovirus has a (+) strand RNA genome.
a) What happens when you infect ViRa and SaSi with poliovirus?
b) What happens when you transfect ViRa and SaSi cells with poliovirus RNA?