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Assume you have two cell lines named ViRa and SaSi growing in your lab. ViRa is susceptible to poliovirus infection, but is not permissive; SaSi is not susceptible to poliovirus infection, but is permissive. Note that poliovirus has a (+) strand RNA genome.

a) What happens when you infect ViRa and SaSi with poliovirus?

b) What happens when you transfect ViRa and SaSi cells with poliovirus RNA?

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