Assume you construct a screening method for cystic fibrosis that allows you to identify the predominant mutation?508 and the next six most prevalent mutations.
What must you consider before using this method to screen a population for this disorder?
Check all that apply.
Check all that apply.
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- the possibility of false negative results in persons who have chromosome number abberations
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- the cost-effectiveness of screening a large population for CF mutations
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- the possibility of false negative results in persons who carry the gene for CF in the form of differently mutated alleles
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- the possibility of false negative results in persons who carry no gene for CF
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- the possibility of false positive results in persons who carry the same mutations in non-coding regions of DNA
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