Assignment: Genetics Lab
Patient Bios
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Kayla
- Age: 35
- Kayla is seeking genetic counseling for muscular dystrophy.
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Emily
- Age: 40
- Emily is seeking karyotype analysis
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Patient Chart
Please use the below chart for navigation to the tests.
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Kayla
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Emily
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Scenario 1 - Pedigree Analysis (Page 2)
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Scenario 2 - Karyotype (Look on Page 5)
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Relationship between 1 and 2
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Gender of Fetus
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Relationship between 1 and 5
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Chromosomal Abnormalites
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Relationship between 1 and 10
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Chromosomal Combination Result
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Relationship between 6 and 7
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Relationship between 4 and 5
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Relationship between 5 and 8
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Relationship between 8 and 10
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Relationship between 1 and 3
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Chances mother is a carrier
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Chances Kayla is a carrier
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Chances Kayla passes the syndrome to male child
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If Kayla is a carrier, what are chances of having an affected child?
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If Kayla is not a carrier, what are chances of having an affected child?
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Kayla has a family history of Duchenne muscular dystrophy (DMD), which is a sex-linked trait. The patient wishes to know her risk of having an affected child. Her grandmother was a known carrier. DMD is an inherited disorder that involves progressive muscle weakness. It affects approximately 1 in 3500 male births worldwide and is inherited in an X-linked recessive pattern.
The following pedigree was drawn up by the genetic counselor. Our patient, Kayla, is #13.
What are the relationships between:
1 and 2 ________________ 1 and 5________________
1 and 10 ________________ 6 and 7_________________
4 and 5 __________________ 5 and 8_________________
8 and 10_______________ 1 and 3__________________
What are the chances her mother was a carrier?
What are the chances our patient is a carrier?
What are the chances she passes the syndrome to a male child?
Testing would establish her status as either a carrier or a noncarrier.
If she is a carrier what are the chance of her having an affected child?
If she is not a carrier what are the chance of her having an affected child?