Which statement about antibiotics and their use is incorrect?
a. Antibiotics are antimicrobial substances that are often synthesized by and isolated from other microorganisms.
b. The targets of antimicrobial activity should be bacterial cell specific.
c. In general, Gram-positive bacteria are more sensitive to ?-lactam antibiotics than are Gram-negative bacteria.
d. Narrow-spectrum antimicrobials are used when the pathogen has not been identified.
e. Acquisition of a conjugative plasmid harboring antibiotic resistance genes is one of the easiest ways for bacteria to develop resistance to antibiotics.