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a) What is the name of an antibacterial antibiotic which stops bacterial DNA replication by inhibiting topoisomerase? Is the answer Quinolones?

b) Why does bacterial DNA replication stop when topoisomerase is inhbited?  

c) A Topoisomerase inhibitor may not only stop bacteria from replicating their DNA but may actually kill the bacteria. How can inhibition of topoisomerase enzyme kill the cell?

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