A man makes 0 units of an enzyme due to homozygous, Ask an Expert

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A man makes 0 units of an enzyme due to homozygous recessive genes on chromosome 21. His wife makes 100 units of the enzyme due to a heterozygous pair of genes on chromosome 21. They have a son with trisomy 21 who makes 200 units of the enzyme.

a. In which parent did the nondisjunction occur?

b. Did the nondisjunction occur in meiosis I or meiosis II (explain your answer)?

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Category:- Biology
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