Ask Question, Ask an Expert


Ask Biology Expert

Exams are approaching quickly and for review, can you please provide the correct answers for the following multiple-choice quiz on human genetics, along with an explanation of the correct answer. Thank you!


1. Red-green color blindness is X-linked in humans. If a male is red-green color blind, and both parents have normal color vision, which of the male's grandparents is most likely to be red-green color blind?

A. maternal grandmother
B. maternal grandfather
C. paternal grandmother
D. paternal grandfather
E. either grandfather is equally likely

2. When RFLP analysis is used to search for a human gene, the strategy is to first locate?

A. a known gene on the same chromosome
B. an homozygous individual with a simple RFLP pattern
C. a DNA sequence anywhere on the same chromosome
D. any DNA marker co-inherited with the genetic trait of interest
E. an exon of the disease gene

3. Human Genome Project Objectives
Which of the following is not one of the objectives of the Human Genome Project?

A. Create a detailed genetic map of every human chromosome, with an average of 2-5% recombination frequency between markers.
B. Obtain a detailed physical map of every human chromosome, based on overlapping recombinant DNA molecules cloned as yeast artificial chromosomes.
C. Clone human beings.
D. Determine the sequence of all expressed human genes by cDNA cloning and sequencing.
E. Determine the complete DNA sequence of each human chromosome.

4. A couple has a female child with Tay Sachs disease, and three unaffected children. Neither parent nor any of the four biological grandparents of the affected child has had this disease. The most likely genetic explanation is that Tay Sachs disease is inherited as a(n) ______________ disease.

A. autosomal dominant
B. autosomal recessive
C. sex-linked recessive
D. sex-linked dominant
E. cannot make a reasonable guess from this information

5. Interpreting a pedigree chart

A human geneticist determined the pedigree shown in the diagram (attachment) with filled symbols showing the affected individuals. How is this pattern of inheritance described?

A. autosomal dominant
B. autosomal recessive
C. sex-linked recessive
D. sex-linked dominant
E. none of these

6. Diagnosis of chromosome aneuploidy of unborn children is normally done by a combination of amniocentesis, cell culture, and _______________.

A. enzyme assay.
B. RFLP analysis.
C. pedigree analysis.
D. karyotyping.
E. somatic cell fusion.

7. Which statement about Down syndrome is false?

A. The frequency increases dramatically in mothers over the age of 40.
B. The cause is a non-disjunction when chromosomes do not separate during the first meiotic division.
C. Affected individuals have an extra autosome.
D. The long time lag between onset of meiosis in ovarian tissue (during fetal development) and its completion (at ovulation) is most likely the reason for increased incidence in older mothers.
E. None, all statements are true.

8. A human male carrying an allele for a trait on the X chromosome is:

A. heterozygous
B. homozygous
C. hemizygous
D. monozygous
E. holozygous

9. Why would you predict that half of the human babies born will be males and half will be females?

A. Because of the segregation of the X and Y chromosomes during male meiosis.
B. Because of the segregation of the X chromosomes during female meiosis.
C. Because all eggs contain an X chromosome.
D. Because, on average, one-half of all eggs produce females.
E. Because of the formation of the Barr body early during embryonic development.

10. Predicting inheritance pattern from pedigree analysis

A man who had purple ears came to the attention of a human geneticist. The human geneticist did a pedigree analysis and made the following observations:

In this family, purple ears proved to be an inherited trait due to a single genetic locus. The man's mother and one sister also had purple ears, but his father, his brother, and two other sisters had normal ears. The man and his normal-eared wife had seven children, including four boys and three girls. Two girls and two boys had purple ears. The purple-ear trait is most probably:

A. autosomal, dominant
B. autosomal, recessive
C. sex-linked, dominant
D. sex-linked, recessive
E. cannot be determined from this information

11. Diagnosis of Klinefelter's syndrome Klinefelter's syndrome (XXY) is an ex of chromosomal aneuploidy that can be readily diagnosed by:

A. Behavioral analysis
B. Somatic cell genetics
C. Karyotyping
D. Biochemical analysis
E. Pedigree analysis

12. By examining a number of somatic-cell hybrid lines for enzyme activities and their human chromosome constitution, scientists can determine

A. on which human chromosome the gene for a particular enzyme is located
B. the number of genes for enzymes in the human genome
C. the number of chromosomes in the human genome
D. the number of human chromosomes in each cell
E. Scientists cannot determine any of these things

13. Which is NOT a common method used in human genetic analysis?

A. pedigree analysis
B. karyotyping
C. RFLP analysis
D. test cross
E. somatic cell genetics

14. A Barr body is:

A. the cause of Down's syndrome
B. an amplified gene
C. a polytene chromosome
D. a ribonucleoprotein particle
E. an inactivated X chromosome

15. Which of the following is a useful marker for genetic or physical mapping of human chromosomes? (More than one answer could be correct)

A. RFLPs, "restriction fragment length polymorphisms"
B. ESTs, "expressed sequence tags"
C. STRPs, "short tandem repeat polymorphisms"
D. STSs, "sequence tagged sites"
E. all of the above

16. Which of the following describes a type of polymorphism that occurs within the gene that causes Huntington's disease?
A. RFLPs, "restriction fragment length polymorphisms"
B. ESTs, "expressed sequence tags"
C. STRPs, "short tandem repeat polymorphisms"
D. STSs, "sequence tagged sites"
E. None of the above

17. Using PCR to detect genetic markers
Which of the following type(s) of polymorphism are commonly detected by using the polymerase chain reaction (PCR) and specific oligonucleotide primers?

A. RFLPs, "restriction fragment length polymorphisms"
B. ESTs, "expressed sequence tags"
C. STRPs, "short tandem repeat polymorphisms"
D. STSs, "sequence tagged sites"
E. B, C, and D are correct

Biology, Academics

  • Category:- Biology
  • Reference No.:- M928036

Have any Question? 

Related Questions in Biology

Mrs smith is 50 years of age and is nervous about going

Mrs. Smith is 50 years of age and is nervous about going through menopause. How would you explain the process to her? What effects do estrogen and progesterone have on the vaginal mucosa? How does the effect of estrogen ...

For this assignment you will select 4 fermented foods to

For this assignment, you will select 4 fermented foods to include in a full course dinner menu. Not every dish in the menu needs to be fermented, but 4 fermented products have to be included. The menu should have an appe ...

Caleb has a lung infection caused by the bacterium

Caleb has a lung infection caused by the bacterium Streptococcus pneumoniae, an extracellular pathogen. What type of adaptive immune response (humoral or cell mediated) will Caleb's immune system have to the bacteria? Su ...

1 much pharmaceutical research targets developing

1. Much pharmaceutical research targets developing anti-cancer drugs that can effectively stimulate the methylation of DNA. Formulate a possible hypothesis to explain why DNA methylation might be an effective anticancer ...

Cell cycle control information cdk is a protein cdk

Cell cycle control information: CDK is a protein. CDK regulate phosphorylation events of mitosis What is a cyclin? What is its relationship to cdks(cyclin-dependent kinases)? How do cyclins work? Which checkpoints are af ...

1 mediterranean climates like those in central california

1. Mediterranean Climates, like those in Central California, experience extremely hot and dry summers and relatively cool and moist winters. Relate the soil-water balance to the growth strategies of plants in this region ...

Digestion is an important process in the human bodya

Digestion is an important process in the human body. a) Identify and describe the digestive processes. b) Consider the mouth, stomach, small intestines and large intestines - identify the digestive enzymes that are prese ...

In hiring a prospective employee there are legitimate

In hiring a prospective employee, there are legitimate reasons for not hiring someone. For example, the prospective employee may not meet legal requirements (i.e., he or she is a minor and cannot complete the tasks of th ...

You have been in hr for 8 years three weeks ago you joined

You have been in HR for 8 years. Three weeks ago you joined your third employer, Chicken Pluckers, Inc., as HR Manager. Chicken Pluckers is a family-owned, meat processing plant with 400 employees. Your new boss, the CEO ...

Bacterial srnas activate and repress translation by

Bacterial sRNA's activate and repress translation by exposing or covering RBS (ribosome binding site) on mRNA. Riboswitches also activate and repress translation by exposing or covering RBS on mRNA. How do these two regu ...

  • 4,153,160 Questions Asked
  • 13,132 Experts
  • 2,558,936 Questions Answered

Ask Experts for help!!

Looking for Assignment Help?

Start excelling in your Courses, Get help with Assignment

Write us your full requirement for evaluation and you will receive response within 20 minutes turnaround time.

Ask Now Help with Problems, Get a Best Answer

WalMart Identification of theory and critical discussion

Drawing on the prescribed text and/or relevant academic literature, produce a paper which discusses the nature of group

Section onea in an atwood machine suppose two objects of

SECTION ONE (a) In an Atwood Machine, suppose two objects of unequal mass are hung vertically over a frictionless

Part 1you work in hr for a company that operates a factory

Part 1: You work in HR for a company that operates a factory manufacturing fiberglass. There are several hundred empl

Details on advanced accounting paperthis paper is intended

DETAILS ON ADVANCED ACCOUNTING PAPER This paper is intended for students to apply the theoretical knowledge around ac

Create a provider database and related reports and queries

Create a provider database and related reports and queries to capture contact information for potential PC component pro