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A group of physiologists, physicians, and climbers went on an expedition to Mt Everest. They tested climbers at extreme altitudes, 5400 m for base camp, and 8850 m at the summit. Some climbers experienced acute mountain sickness affecting the lungs as HAPE. The reason that someone with HAPE would have shortness of breath is that the pulmonary ____ causes an _____ of the ______ for oxygen across the respiratory membrane. Otherwise the homeostatic respond to high-altitude hypoxia is herventilation, which begins on arrival.

What happens to plasma pH during hyperventilation? When applying the law of _____ relating CO2 and H2O reactions and the enzyme ____, there will be a shift in equilibrium of the reaction such that H+ concentration ____, generating a condition called ____. With reference to the figure there would be a _____ compensation causing an increased excretion of _____.

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