(Answered) A 55 yo male presents to your clinic for a scheduled

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A 55 y/o male presents to your clinic for a scheduled follow-up. He has a 15 year history of type 2 diabetes with HbA1c of 8, hypertension, hyperlipidemia, and CAD with a MI last year. You understand that this uncontrolled diabetes is associated with the HTN, HLD, and CAD/MI.

Which statement below best describes this association of diabetic vascular complications?

Inflammatory induced cytotoxic T-lymphocytes leads to degredation of the endothelial wall
Inflammatory induced inhibitor of vascular endothelial growth factors (VEGFs) at eh basement membrane
Vascular smooth muscle in the extracellular matrix (ECM) is inhibited by chronic hyperglycemia
Hyperglycemic enhanced formation of advanced glycation end products (AGEs) setting off a cascade of vascular inflammatory events

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