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1. Which karyotype(s) shows a "normal" male individual (i.e., a male individual with no aneuploidies)?

A. A and B
B. B only
C. C only
D. D only
E. A, B, C & D

2. Which karyotype(s) shows an individual with Turner's syndrome?

A. A only
B. C only
C. B and C
D. D only
E. A and D

3. Fertilization normally takes place in which structure?

A. the vagina
B. the uterus
C. an oviduct
D. the endometrium
E. an epididymis

4. The organ of sexual stimulation and pleasure in the female reproductive system is the:

A. uterus
B. ovary
C. vagina
D. clitoris
E. vulva

5. In the human female, a blastocyst implants into the:

A. uterus
B. oviduct
C. vagina
D. ovary
E. cervix

6. Which extraembryonic membrane contains a fluid that surrounds and bathes the embryo?

A. yolk sac
B. allantois
C. amnion
D. umbilical cord
E. chorion

7. Immediately after fertilization, the zygote begins to

A. expand as it fills with water
B. disintegrate
C. travel through the oviduct back towards the ovary
D. divide by cleavage
E. become a polar body

8. During the formation of an embryo, a solid ball of cells is termed a

A. blastula
B. gastrula
C. neurula
D. fetus
E. morula

9. Fetal development begins with the

A. first month
B. first week
C. third month
D. sixth month
E. seventh month

10. The organ that receives the penis during sexual intercourse is the

A. ovary
B. uterus
C. vagina
D. oviduct
E. follicle

11. The sex chromosome composition of a person with Klinefelter syndrome is

A. XXX
B. XO
C. XXY
D. XYY
E. XX

12. Down syndrome involves trisomy of chromosome

A. 3
B. 5
C. 15
D. 19
E. 21

13. The body cells of a normal human male contain _____ chromosomes.

A. 22
B. 46
C. 92
D. 21
E. 47

14. From which germ layer does the nervous system develop?

A. mesoderm
A. ectoderm
B. endoderm

15. If a human inherits two X chromosomes, the person will (normally) be

A. a female
B. a male
C. color-blind
D. sterile
E. sick

16. Which of the following chromosomal abnormalities could NEVER be observed in an adult human?

A. trisomy 21
B. trisomy X (XXX)
C. trisomy 6
A. Monosomy X (XO)
B. Klinefelter's syndrome (XXY)

17. The building blocks of a nucleic acid like DNA are called

A. amino acids
B. nucleotides
C. glycerol
D. fatty acids
E. polysaccharides

18. Which of the following is composed of glucose subunits?

A. protein
B. fat
C. RNA
D. glycogen
E. DNA

19. A cell's plasma membrane is composed of

A. cellulose
B. cellulose and protein
C. lipid only
D. phospholipids and proteins
E. DNA and RNA

20. Blood belongs to which tissue type?

A. epithelial
B. connective
C. muscular
D. nervous
E. Blood is an organ, not a tissue

21. What general tissue type is responsible for lining and protecting the body?

A. epithelial
B. connective
C. muscular
D. nervous
E. smooth muscle

22. Which type of tissue responds to stimuli and transmits impulses?

A. epithelial
B. connective
C. muscular
D. nervous
E. cardiac

23. The primary function of the large intestine is

A. storage of feces
B. digestion of fats
C. secretion of bile
D. secretion of acid
E. absorption of water

24. Of the following digestive organs, the greatest amount of nutrient absorption takes place in the:

A. stomach
B. small intestine
C. mouth
D. pancreas
E. esophagus

25. The human vocal cords are located in the

A. glottis
B. pharynx
C. trachea
D. larynx
E. bronchus

26. Which of the following is NOT filtered from the bloodstream in the nephron?

A. water
B. red blood cells
C. urea
D. glucose
E. amino acids

27. Filtration of the blood in the kidney takes place in the

A. Loop of Henle (loop of the nephron)
B. Glomerulus
C. Distal convoluted tubule
D. Proximal convoluted tubule
E. Collecting duct

28. The atomic weight (or mass) of an atom is determined by the weight of

A. neutrons and protons
B. neutrons and electrons
C. protons and electrons
D. protons only
E. neutrons only

29. The pulmonary trunk carries blood away from the

A. aorta
B. right atrium
C. right ventricle
D. left atrium
E. left ventricle

30. Erythrocytes are derived from stem cells located in the

A. spleen
B. thymus
C. bone marrow
D. pancreas
E. liver

31. Which of the following would NOT be considered part of the central nervous system?

A. brain
B. cerebellum
C. medulla
D. spinal nerves
E. brainstem

32. Which of the following are the primary cellular sites for the production of proteins?

A. Golgi bodies
B. ribosomes
C. mitochondria
D. lysosomes
E. smooth ER

33. The part of the brain that controls the basic responses necessary to maintain life processes (breathing, heartbeat) is the

A. cerebral cortex
B. cerebellum
C. cerebrum
D. corpus callosum
E. medulla oblongata

34. Photoreceptors are located in the

A. lens
B. cornea
C. pupil
D. iris
E. retina

35. The hormone insulin is produced by the

A. adrenal cortex
B. adrenal medulla
C. thyroid
D. kidneys
E. pancreas

36. Which gland secretes testosterone?

A. testes
B. adrenal medulla
C. thyroid
D. kidney
E. pancreas

37. The adrenal medulla produces

A. insulin
B. epinephrine
C. TSH
D. ACTH
E. testosterone

38. The passageway that allows eggs from the ovary to travel to the uterus is known as

A. A vagina
B. A uterus
C. An oviduct
D. An endometrium
E. A vas deferens

39. The black, central portion of the eye is called the:

A. Retina
B. Pupil
C. Cornea
D. Iris
E. Cone

40. In the condition known as testicular feminization (or CIAS),

A. A person appears male but is XX
B. A person appears female but has two Y chromosomes
C. A person appears male and is XY
D. A person appears female but is XY
E. A person with Turner's syndrome appears male

41. The last structure air moves through before it reaches the alveoli is the

A. larynx
B. glottis
C. pharynx
D. trachea
E. bronchioles

42. The normal pH of the blood is about

A. 3.2
B. 8.5
C. 1.1
D. 7.4
E. 6.3

43. The long bone in the upper leg is called the

A. fibula
B. femur
C. humerus
D. tibia
E. tibula

44. Which cells produce and secrete antibodies that cause the destruction of bacterial invaders?

A. phagocytes
B. macrophages
C. B cells
D. T cells
E. thrombocytes

45. Calcium ions in muscle cells are stored in

A. vacuoles
B. sarcoplasmic reticulum
C. mitochondria
D. actin
E. acetylcholine

46. Which of the following can be defined as the contractile unit of a muscle cell?

A. myofibril
B. myosin filament
C. sarcomere
D. actin filament
E. calcium ion

47. In the sliding filament model of muscle contraction, which two proteins are "sliding" with respect to each other?

A. troponin and tropomyosin
B. actin and myosin
C. sarcomere and myoglobin
D. actin and calcium
E. myosin and troponin

48. The collarbone is officially called the

A. hyoid
B. patella
A. scapula
B. clavicle
C. phalanx

49. The part of the brain that controls the basic responses necessary to maintain life processes (breathing, heartbeat) is the

A. cerebral cortex
B. cerebellum
C. cerebrum
D. corpus callosum
E. brainstem

50. The sense based on air vibrations is

A. taste
B. smell
C. touch
D. sight
E. hearing

51. In human females one of the sex chromosomes is switched off early in development to become a Barr body. This phenomenon is called

A. karyotyping
B. dosage compensation
C. X linkage
D. crossing over
E. mutation

52. Chromosomes other than those involved in sex determination are known as

A. nucleosomes
B. heterosomes
C. alleles
D. autosomes
E. liposomes

53. Which statement is NOT true about the male and female reproductive systems?

A. Males produce greater number of gametes than women do.
B. Women do not have to experience orgasm to become pregnant.
C. The maturation of sperm occurs in the epididymis.
D. They both produce follicle-stimulating hormone.
E. Male and female gametes almost always meet in the vagina.

54. After the zygote begins to divide, what is the next structure formed during the developmental process?

A. A blastocyst
B. A morula
C. A gastrula
D. An embryo
E. A fetus

55. Sperm MATURE in which structure?

A. Testes
B. vas deferens
C. epididymis
D. prostate gland
E. penis

56. Which molecule is composed of amino acid subunits?

A. DNA
B. RNA
C. Protein
D. enzyme
E. fat

57. Food is prevented from entering the trachea by the

A. epiglottis
B. larynx
C. pharynx
D. esophagus
E. stomach

58. The "80" in a blood pressure of 120/80 is the

A. Diastolic pressure
B. Systolic pressure
C. Pulse pressure
D. Capillary pressure
E. Venous pressure

59. Which of the following conditions is characterized by a karyotype with 45 chromosomes?

A. Turner syndrome
B. Down syndrome
C. testicular feminization
D. Klinefelter syndrome
E. Huntington's disease

60. Which of the following conditions is characterized by a karyotype with 47 chromosomes?

A. Turner syndrome
B. cri-du-chat syndrome
C. testicular feminization
D. Klinefelter syndrome
E. Huntington's disease

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