1. What is the study system?

General information. E.g. What is a "cell line"? Include images.

2. Why would a researcher use this study system?

The particular features of this system that make it useful. E.g. cell lines allow the study of genetically identical cells in many labs

3. What type of research questions can this study system be used to help answer?

List a few examples of research questions or general areas of research that can be addressed using this system. Elaborate a little on each, so we understand what you mean.

4. How does a researcher typically use this system?

What are the logistics of it? E.g. basic information about how they culture and propagate cell lines.

5. What are the pros and cons of this study system?

List and briefly explain any drawbacks or caveats that we should be aware of, along with particular benefits E.g. mammalian cell lines need adequate facilities and resources to be propagated, but they also allow for the study of mammalian cellular systems in vitro instead of studying another eukaryote like yeast.

6. Are there alternatives or variations on this study system?

If you can't use this particular study system, what are your options for alternatives? E.g. Use yeast as a representative of a eukaryotic cell.

7. What is a real example from primary literature of this study system being used?

Provide a brief summary of the research that used the study system of interest, including the main objective, basic methods used, the main results, and conclusions. Include an image of at least one figure or table, along with an explanation of what that figure/table illustrates. You must provide the complete citation of the paper and/or a link to the online paper.

8. List of sources and places where we can find more information.