(Answered) 1 what is the mutation how does this mutation impact dna

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1. What is the mutation, how does this mutation impact DNA replication?

2. How was the relationship between the mutation and the disease discovered?

3. What are the symptoms of the disease?

4. How does the problem in DNA replication lead to the symptoms of the disease (a discussion of transcription and/or translation may be appropriate here)?

5. How could genetic engineering technology be used to learn more about this disease?

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