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1. In what ways does activation of complement affect our immune responses and name 3? Why may complement not be activated in a person who has AIDS?

2. MADGE is an acronym that helps us remember the 5 classes of antibodies.

A. Which class(es) activate complement?

B. Which class(es) may function as B cell receptors? Which class(es) cross the placenta?

C. Which antibody is produced first in response to a challenge?

D. Which antibody class do we have the most antibodies from? Name one

3. Describe two ways innate immune system function is compromised in AIDS patients who have a low helper T cell count.

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