Given that acetyl-CoA can be made from virtually any fuel source in the body, what impact would dietary reduction of cholesterol have on overall cholesterol levels? At what point in the cholesterol synthesis pathway do statins operate?
Why is modulating ligand concentration not sufficient for adequate control of signaling in an organism? Sketch a diagram of a G-protein coupled receptor cascade, and indicate the possible actions that can be taken by a cell to inhibit the signal.