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High-altitude adaptation. After spending a day or more at high altitude (with an oxygen partial pressure of 75 torr), the concentration of 2,3-bisphosphoglycerate (2,3-BPG) in red blood cells increases. What affect would an increased concentration of 2,3-BPG have on the oxygen-binding curve for hemoglobin. Why would this adaptation be beneficial for functioning well at high altitude?

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