Uric acid dissociates as shown in the figure at the right with a pKa of 5.80, and can be treated as a simple monoprotic acid in this pH range. Its solubility in urine depends on the relative amount of protonated and unprotonated forms. A urine sample was found to have a pH of 6.76.
What would be the ratio of the unprotonated form, A-, to the protonated form, HA, for uric acid in this urine sample?
[A-]/[HA]=
What would be the fraction of the uric acid in the neutral, protonated form in this sample?
Fraction as HA=