Ask Question, Ask an Expert

+1-415-315-9853

info@mywordsolution.com

Ask Chemistry Expert

Chemistry of Proteins and Hemoglobin.

1. Protein A has a binding site for ligand X with a Kdof 10-6M. Protein B has a binding site for ligand X with a Kdof 10-9M. Which protein has the higher affinity for ligand X?

2. What is the effect of the following changes on the O2 affinity of hemoglobin? (a) A decrease in blood pH from 7.4 to 7.2. (b) A decrease in the partial pressures of CO2in the lungs from 6 kPa (holding one\'s breath) to 2 kPa (normal). (c) An increase in the BPG level from 5 mM (normal altitudes) to 8 mM (high altitudes). For (c), also consider fetal hemoglobin.

3. Under appropriate conditions, hemoglobin dissociates into its four subunits. The isolated α subunit binds oxygen, but the O2-saturation curve is hyperbolic rather than sigmoid. In addition, the binding of oxygen to the isolated α subunit is not affected by the presence of H+, CO2, or BPG. What do these observations indicate about the source of the cooperativity in hemoglobin?

Chemistry, Academics

  • Category:- Chemistry
  • Reference No.:- M919265

Have any Question? 


Related Questions in Chemistry

What mass of nah2po4 must be added to 120 l of 020 m

What mass of NaH 2 PO 4 must be added to 1.20 L of 0.20 M Na 2 HPO 4 to make a buffer solution whose pH=6.90? pK a2 (H 3 PO 4 )=7.21.

When 0430 mole of titanium is combusted in a bomb

When .0430 mole of titanium is combusted in a bomb calorimeter, the temperature of the calorimeter increases from 30.00degress Celsius to 91.60 degrees Celsius. In a separate experiment, the heat capacity of the calorime ...

Simple cubic packing when r mno has either nacl type

Simple Cubic Packing when r+ MnO has either NaCl type structure or the CsCl type structure. The edge length of the MnO unit cell is 4.47 x 10-8 cm and the density of MnO is 5.28 g/cm3. A) Does MnO crystallize in the NaCl ...

The combustion of so2g has keq560x104 at 350 degrees

The combustion of SO2(g) has Keq=5.60x10^4 at 350 degrees Celcius. If 0.350bar of SO2(g) and 0.762bar of O2(g) are mixed initially, what are the partial pressures of each of the three gases when the mixture reaches equil ...

1reacting molecules or ions in a solution at room

1. Reacting molecules or ions in a solution at room temperature are in constant motion and collide. Some collisions lead to formation of product and some don't. what determines a reaction will take place. 2. Is there any ...

Calculate the amount of work done for the conversion of 100

Calculate the amount of work done for the conversion of 1.00 mole of Ni to Ni(CO)4in the reaction below, at 75oC. Assume that the gases are ideal. The value of R is 8.31 J/molK.

Write a reserch paper on gas chromatographythis is a 10

Write a reserch paper on Gas chromatography. This is a 10 pages research paper that should include an introduction on chromatography, principles of separation, type of columns, resolution, detection methods and applicati ...

Determine the mass of glucose c6h12o6s needed to produce a

Determine the mass of glucose, C6H12O6(s), needed to produce a 0.150m glucose solution in 50.0mL of C2H5OH(l), density 0.789g/mL

Potassium and sodium chloride are similar in charge and

Potassium and sodium chloride are similar in charge and they both have the same anion. When comparing sodium chloride (36 g / 100 mL at 0 oC) and potassium chloride, which has a higher solubility at 0 oC?

Calculate the increase in the boiling point deltat for a

Calculate the increase in the boiling point, ΔT, for a 1.87 m solution of sucrose (dissolves as a molecule) in water.

  • 4,153,160 Questions Asked
  • 13,132 Experts
  • 2,558,936 Questions Answered

Ask Experts for help!!

Looking for Assignment Help?

Start excelling in your Courses, Get help with Assignment

Write us your full requirement for evaluation and you will receive response within 20 minutes turnaround time.

Ask Now Help with Problems, Get a Best Answer

WalMart Identification of theory and critical discussion

Drawing on the prescribed text and/or relevant academic literature, produce a paper which discusses the nature of group

Section onea in an atwood machine suppose two objects of

SECTION ONE (a) In an Atwood Machine, suppose two objects of unequal mass are hung vertically over a frictionless

Part 1you work in hr for a company that operates a factory

Part 1: You work in HR for a company that operates a factory manufacturing fiberglass. There are several hundred empl

Details on advanced accounting paperthis paper is intended

DETAILS ON ADVANCED ACCOUNTING PAPER This paper is intended for students to apply the theoretical knowledge around ac

Create a provider database and related reports and queries

Create a provider database and related reports and queries to capture contact information for potential PC component pro