Tricostatin a tsa is a protein deacetylase inhibitor you, Ask an Expert

Academics

Tricostatin A (TSA) is a protein deacetylase inhibitor. You know that HDACs remove acetyl groups from lysines. You are interested in identifying how TSA works. You do a number of experiments. You find the level of a protein, called survivin is increased 10-fold in cells when you treat with TSA. You assume this is at the level of transcription. You measure the mRNA for survivin and find it is unchanged. Can you think why TSA increased survivin protein?

View complete question

Chemistry, Academics

Category:- Chemistry
Reference No.:- M91519179

Have any Question?Write your Review or question?

Related Questions in Chemistry

You will have a 500ml solution of salt water from this you

You will have a 500mL solution of salt water. From this you will take 10.0mL and place it on a balance. You find that the 10.0mL solution has a mass of 12.5 g. What is the density of the 500mL of salt water solution in g ...

Calculate the volume of 60m naoh solution that you would

Calculate the volume of 6.0M NaOH solution that you would need to prepare 500mL of a .15M NaOH solution. (formula weight of NaOH = 40.00g/m)

An aqueous solution has a normal boiling point of 1020degc

An aqueous solution has a normal boiling point of 102.0°C. What is the freezing point of this solution? For water K b is 0.51°C/ m and K f = 1.86°C/ m.

When 514g of biphenyl c12h10 undergoes combustion in a bomb

When .514g of biphenyl (C12H10) undergoes combustion in a bomb calorimeter, the temperature rises from 25.8 degrees C to 29.4 degrees C. Find delta E(rxn) for the combustion of biphenylin kJ/mol. The heat capacity of the ...

Ttrate the base trimethylamine tma with 0126 m hcl ch3naq

Titrate the base trimethylamine (TMA) with 0.126 M HCl. (CH) 3 N(aq) + H 2 O(l) (CH 3 ) 3 NH+(aq) + OH-(aq) Kb = 6.45 x 10 -5 There are 0.00615 moles of TMA in 42.5 mL H 2 O before titration begins. What percent of TMA i ...

An analysis of an oxide of nitrogen with a molecular weight

An analysis of an oxide of nitrogen with a molecular weight of92.02 amu gave 69.57% oxygen and 30.43 % nitrogen. What is the empirical formula of the compound?

A chemist adds 3700 ml of a 0371m barium acetate bac2h3o22

A chemist adds 370.0 mL of a 0.371M barium acetate (Ba(C2H3O2)2) solution to a reaction flask. Calculate the millimoles of barium acetate the chemist has added to the flask. Round your answer to 3 significant digits.

A 43 kg person drinks 430 g of milk which has a caloric

A 43 kg person drinks 430 g of milk, which has a "caloric" value ofapproximately 3.0 kJ/g. If only 15% ofthe energy in milk is converted to mechanical work, how high (inmeters) can the person climb based on this energy i ...

A 479 ml sample of 09833 m hcl is mixed with 485 ml sample

A 479 mL sample of 0.9833 M HCl is mixed with 485 mL sample of NaOH (which has a pH of 13.48). What is the pH of the resulting solution?

Calculate the volume in milliliters of anbsp18 moll ironii

Calculate the volume in milliliters of a 1.8 mol/L iron(II) bromide solution that contains 150.g of iron(II) bromide FeBr2. Round your answer to 2 significant digits.

4,153,160 Questions Asked
13,132 Experts
2,558,936 Questions Answered

Ask Experts for help!!

Looking for Assignment Help?

Start excelling in your Courses, Get help with Assignment

Write us your full requirement for evaluation and you will receive response within 20 minutes turnaround time.

Ask Now Help with Problems, Get a Best Answer

Recent Questions

Ask Chemistry Expert