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The compound malonate is an analog of succinate and is a strong inhibitor of succinate dehydrogenase. The active site of the enzyme will bind to either molecule, however malonate will not undergo any reaction and gets stuck on the enzyme.

Having this in mind answer the following questions with explanation

A) How many NADH's will be produced from the introduction of a single pyruvate molecule to the mitochondrion that is poisoned with malonate (assume that there are adequate amounts of all needed substances)?

B) How many FADH2's will be produced from the introduction of a single pyruvate molecule to the mitochondrion that is poisoned with malonate (assume that there are adequate amounts of all needed substances)?

C) How many ATP's will be produced from the introduction of a single pyruvate molecule to the mitochondrion that is poisoned with malonate (assume that there are adequate amounts of all needed substances)?

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  • Category:- Chemistry
  • Reference No.:- M9496519

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