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Question- A polymer graft is incubated in a large container of plasma solution containing albumin (40 mg/ml), fibrinogen (2 mg/ml) and globulin (4.6 mg/ml). The diffusion coefficients of these protein molecules are 6.1x10-7 cm2/s (albumin), 2.0x10-7 cm2/s (fibrinogen) and 4.1x10-7 cm2/s (globulin).

(1) Within 30-second incubation time, which protein adsorbs the most on the graft surface? Why?

(2) How will you answer to (1) change if the graft is incubated with a pure solution of fibrinogen at a concentration of 20 mg/ml?

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