Question - from distribution studies species m and n are, Ask an Expert

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Question - From distribution studies, species M and N are known to have distribution constants between water and hexane of 6.01 and 6.20(K=?M?H2O/?H?hex). The two species are to be separated by elution with hexane in a column packed with silica gel containing absorbed water. The ratio VS/VM for the packing is known to be 0.422.

(a) Calculate the retention factor for each of the solutes.

(b) Calculate the selectivity factor.

(d) How long a column is needed if the plate height of the packing is 2.2×10-3cm.

(e) If a flow rate of 7.10 cm/min is employed, what time will be required to elute the two species?

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