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Problem- A critical reaction in the production of energy to do work or drive chemical reactions in biological systems is the hydrolysis of adenosine triphosphate, ATP, to adenosine diphosphate, ADP, as described by

ATP (aq)+ H20 (l) ->ADP (aq) + HPO4 (negative two overall charge) (aq).

For which ?G°rxn = -30.5 kJ/mol at 37.0 °C and pH 7.0. Calculate the value of ?Grxn in a biological cell in which [ATP] = 5.0 mM, [ADP] = 0.90 mM, and [HPO42-] = 5.0 mM.

A. What is the delta G rxn in kJ/mol?

B. Is the hydrolysis of ATP spontaneous under these conditions?

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  • Category:- Chemistry
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