Problem- 1. A molecule with a chiral center must be optically active whereas a molecule with two chiral centers may or may not be optically active. Explain and provide examples.

2. Imagine meta-xylene with -NO2 and -NH2 groups attached as substituents to its benzene ring. If the -NO2 group is directly between the meta-xylene methyl groups and the -NH2 group is para to the -NO2 group, significantly different Bronstead Lowery basicity is observed for the -NH2 group than if the -NH2 group is directly between the meta-xylene methyl groups and the -NO2 group is para to the -NH2 group.

-Explain with lewis structure analysis and resonance effects. *Hint: Consider steric effects too*

Articulate your answer to two significant figures as well as comprise the appropriate units.