Patient recently dx and treated for pyelonephritis. Then dx with pnuemonia and currently on augmentin 875/125mg orally every 12 hours for 10 days.

Upon receipt of laboratory results, you notice that his eGFR is ~40mL/min, his serum creatinine is 3.0 mg/dl, and his BUN is 50 mg/dl. 

• How will the medication regimen(s)(augmentin 875/125mg orally every 12 hours for 10 days) have to be adjusted given these new laboratory findings, and how should you be monitoring for efficacy and toxicity of this patient's pharmacological profile with a summary of where this patient currently stands in his medical treatment?

Substantial answer--less than a page.

References within 5 years.